04/25/2010
Melan-A Control
Also known as MART-1, for Melanocytic Antigen Recognized by cytotoxic T lymphocytes from melanoma patients, it is a sensitive and specific cytoplasmic protein for melanoma. It is used to diagnose metastatic disease and evaluate sentinel lymph nodes for melanoma.
Similar Cases
04/25/2010
S-100is structurally similar to calmodulin and gets its name from the fact that it is 100% soluble in ammonium sulfate at neutral pH.
04/25/2010
PAS stains glycogen as well as mucins, but tissue can be pre-digested with diastase to remove glycogen. It stains neutral and acid-simple non-sulfated and acid-complex sulfated mucins.
04/25/2010
Mucicarmine contains carmine (red coloring material) and aluminum chloride and is very specific for epithelial mucins, including adenocarcinomas.
Comments
Hi I have a case, lymphnode, which is CD45+, S100+,HMB45-. and the clinical specter goes for lymphoma. Can S100 be strongly positive in lymphoma