07/21/2010
Liver failure with cholestasis and OLT
A 16-year-old, Jehovah's witness, African-American female presented with a 4-month history of increasing right upper quadrant abdominal pain, jaundice, fatigue, ascites, and hepatomegaly. She underwent orthotopic liver transplantation due to irreversible liver failure. The explanted liver was markedly enlarged, deeply cholestatic (gross image) and showed concentric stricture of the common bile duct (gross image - red arrow). Microscopic sections of the bile duct are submitted (H&E low and high magnifications and S-100 immunostain)
- Case Overview
- Diagnosis
Comments
good case have not seen one in my practice, gross pictures are have clarity .thanks for sharing.
Nice case
Such cases are seen ones in Life time.Very good Gross photograpgh.
Excellent .
Thank you so much
Very interesting; nice gross photograph, too.
very interesting indeed.
very interesting indeed.
Granular cell (Abrikosof) tumor. A nice case. I saw such tumors in the breast, uterine tube, larinx. The case like this was described in Russian "Annals of Hepathology".
Very nice case and good pics
Thanks. Interesting.
very good case
Thanks a lot for sharing such a rare case, excellent pictures.
a very nice case and i have seen this for the first time
very nice pictures,specially immunostaining,it's the first time i see this tumor in biliary tract
very nice pictures. Thanks for sharing them. In veterinary medicine, granular cell tumors (GCTs) are rare in domestic animals. to my knowledge no report of GST in liver in animals. GSTs have been reported most commonly in dogs and horses, and there are several reports describing GCTs in cats and a bird. Primary GCTs occur at several sites in the body, and in dogs these tumors are most commonly described in the oral cavity. Additionally, canine GCTs have been reported occasionally at other sites such as heart, lymph node, brain, and skin and rarely involving the central nervous system of any species. They are not always S-100 positive.
good case, nice pictures
I agree with Rhonda. Very unusual case and excellent gross photos especially.
The gross photos in this case are amazing--thanks for sharing it.
See Reference.
Gastroenterol Hepatol (N Y). 2010 May;6(5):331-6.
Granular cell tumor of the biliary tract.
Patel AJ, Jakate SM.
Department of Pathology, Rush University Medical Center, Chicago, Illinois.