4.333335
Average: 4.3 (9 votes)
Brain tumor
09/26/2012
KazmiSan Antonio Military Medical Center
Tags: Neuropathology   Ependymoma   Glioma   brain tumor   
77-year-old female with a contrast-enhancing brain tumor.
Age:
77
Sex:
female
Condition:
Brain tumor.
History:
77-year-old right-handed female with history of a recent fall. She denies any loss of consciousness. In further evaluation, a CT of the chest, abdomen, and pelvis were performed and showed a solid left renal mass measuring 3.8 cm suspicious for a renal cell carcinoma. MRI of the brain on showed a 4.5 x 4.3 x 4.1 cm contrast-enhancing mass (Image 1) with midline shift and extensive edema. She underwent an image guided craniotomy and near-total resection.
Note:
Microscopic examination demonstrates a glial tumor forming abundant perivascular pseudorosettes (Image 2-4). Neoplastic cells are round to oval with eosinophilic to clear cytoplasm. Neoplastic nuclei are vesicular; some with small nucleolus. Mitoses are very rare. There is no vascular endothelial proliferation. Necrosis, without pseudopalisading, is identified.

Immunostaining for GFAP (Image 5) is diffusely positive in tumor and highlighted the perivascular cell processes. Immunostaining for EMA is negative except for cytoplasmic staining in rare cells. Immunostaining for Ki-67 shows a low proliferation index (1-2%).
    Tumor 1 5 201209...
    Image 9
    Image 1
    Image 5
    Image 4
    Image 3
    Image 6
    Image 2
    Image 7
    Image 8
    Image 6
    Image 7
    Image 8
    Image 9
    Image 10

    Comments

    23/06/14
    I love this article and its
    AnnesStar Imaging And Path Lab
    5
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    13/03/13
    chemotherapy
    sabereevesFoundation
    0
    the female though she have brain tumor but in contrast, at least she may have already enjoy the life. at this stage of 77 years old, i guess she can't ask for more. perhaps she just take the medication and hoping it will cure the tumor. more plays on soundcloud
    07/12/12
    brain tumour
    essaa1lancet labs
    0
    viewed a similar case just 2 weeks ago, similar but lacking the apparent tapered processes. think its an astroblastoma.
    02/12/12
    This case is really
    SakinaYenepoya Medical College
    4
    This case is really interesting.. Conventionally we are tought of adeno ca. This is different.. Thanks for the info..
    30/11/12
    Great case
    malyousef85Dammam University
    4
    Thank you for sharing
    30/11/12
    hi
    sumanthkdevaosmania medical college
    4
    thanks
    28/11/12
    So grateful for sharing this interesting case
    ban qasimMedical College/Al-Nahrain University,Baghdad,Iraq
    0
    Ependymoma
    28/11/12
    Hi
    MontazerMashhad University of Medical Sciences
    0
    The coincidence is so interesting. Thanks. ... Now, how about performing a needle biopsy of the renal mass, instead of a surgical resection?
    27/11/12
    ependymoma
    mohqubatiTaiz University
    0
    ependymoma
    26/11/12
    Ependymoma
    skazmiUNMC
    0
    Patient decided not to pursue her renal tumor surgically at this time. She will be followed by serial immaging.
    26/11/12
    ependymoma
    threeyanadr soetomo hospital
    4
    wow....ependymoma... how about her renal mass ?
    26/11/12
    Ependymoma
    AzzanazarAljomhori hospital
    0
    Ependymoma
    26/11/12
    Ependymoma
    dbhansaliUC Irvine
    0
    Ependymoma
    20/11/12
    Great case Dr. Kazmi.
    4
    Great case Dr. Kazmi.
    16/11/12
    Thanks for giving information
    JessicaGreenTempocreative
    4
    Thanks for giving information about Brain tumor.