10/16/2009
Neck Mass
3 year old boy with a posterior neck mass.
Gross: The specimen is consists of multiple pink-tan, firm, irregular tissue fragments, measuring 0.1 to 0.4 cm. in greatest dimension. All submitted with decalcification.
Micro: Sections show fragments of ghost cells with no visible epithelial component. Patchy fibrosis, calcifications, areas of ossifications, and giant cell proliferation are present. H&E Stain.
- Case Overview
- Diagnosis
Age:
3
Sex:
male
History:
Posterior neck mass.
Note:
H&E Stain.
| Attachment | Size |
|---|---|
| Image463.jpg | 1.4 MB |
| Image464.jpg | 1.11 MB |
| Image465.jpg | 1.16 MB |
| Image466.jpg | 1.21 MB |
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Comments
nice example of pilomatrixoma with ossification
Pilomatrixoma.
pilomatricoma
In a recent study 75% of these lesions had mutations in the gene CTNNB1; which directly implicate beta-catenin/LEF misregulation as the major cause of hair matrix cell tumorigenesis (Pilomatricoma).
In a recent study 75% of these lesions had mutations in the gene CTNNB1; which directly implicate beta-catenin/LEF misregulation as the major cause of hair matrix cell tumorigenesis (Pilomatricoma).
Pilomatrixoma. Nice pictures.
pilomatricoma