Brain

50-year-old female with headache, right hemiparesis, and a left temporal lobe neoplasm.

Procedure: Craniotomy, removal of neoplasm from left temporal lobe.

Gross: The specimen consists of irregu

34 years female presented with progressive headache with episodes of vertigo.
Clinical Diagnosis - left frontoparafalcine glioma.
MRI : s/o left frontal solid cystic ICSOL.

- One H&E stained sect

This malignant neoplasm is composed of large neoplastic lymphocytes. CD-45, CD-20, and CD-45RO are positive. CD-3 is negative.

A 39 yr old man presented with an epileptic seizure. Imaging revealed an ICSOL in the temporal region involving the bone and suggestive of an Epidermoid cyst.

2 H&E stained sections are provided.

Sections show a pilocytic glial neoplasm with sparse Rosenthal fibers and more frequent eosinophilic granular bodies.

Since the gangliocytes are dysplastic and largely limited to the granular layer of the cerebellum, the lesion is compatible with Lhermitte-Duclos Disease.

The EMA stain is focally positive. The Ki-67 stain shows a low proliferative rate (<1%).